Sodium acetate

Drug ingredientActive Shortage

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

Molecular structure of 127-09-3
US ProductionCBI
Import Value$64M
Top SourceNetherlands 37%

The EPA did not publish how much of this chemical companies made or imported, or marked that amount confidential. Without that volume, ACID cannot calculate import dependency.

Where It Comes From

Customs basis: HS 291529 · basket

These shares come from HS customs code 291529, which covers 18 chemicals in total. They estimate the bucket's origin mix, not this chemical specifically.

Source Countries
NL 37%NetherlandsCN 16%ChinaCA 15%CanadaIT 7%ItalyGB 5%United Kingdom
EPA-registered manufacturers (6)
Avantor
General Atomics International Services
Harcros Chemicals
Hawkins
Kemira Chemicals
Show all 6
Niacet
EPA-registered importers (4)
Colonial Group
Global Chemical Resources
Tfl Usa/Canada
Western Reserve Chemical
13 FDA-registered drug labelers
Alcon Laboratories, Inc.
Avantor Performance Materials, LLC
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
Fenwal, Inc.
Fresenius Kabi USA, LLC
Hahnemann Laboratories, INC.
Jost Chemical Co
Macco Organiques Inc
Merck KGaA
Merck Life Science Technologies (Nantong) Co., Ltd.
MILLA PHARMACEUTICALS INC.

Why It Matters

Sectors
Core ChemicalsHealthFoodEnergyPlastics & RubberConsumer ProductsTextiles
Downstream Uses

Appears in 17 drug and cosmetic product listings (FDA).

  • •Sodium Acetate
  • •Natrum Aceticum
  • •Isolyte S
  • •Kabiven
  • •Plasma-Lyte 148 (pH 7.4)
  • •Solucion InterSol
  • •Isolyte P in Dextrose
  • •Clinimix E
Show all 17
  • •InterSol
  • •Multiple Electrolytes pH 5.5
  • •Multiple Electrolytes pH 7.4
  • •Plasma-Lyte A
  • •BSS
  • •Isolyte S pH 7.4
  • •Balanced Salt
  • •Physiolyte
  • •Perikabiven
FDA Shortage Status
Active Shortage
Shortage History
current

Sodium Acetate Injection

02/03/2016

Unavailable

current

Sodium Acetate Injection

03/23/2016

Available

current

Sodium Acetate Injection

02/03/2016

Limited Availability

current

Sodium Acetate Injection

02/03/2016

Available

Industrial Uses

Used in 8 sectors as 7 functional roles.

  • •pH regulating agent in Oil and Gas Drilling, Extraction, and Support activities (30%)Use—non-incorporative activities
  • •Catalyst in Not Known or Reasonably AscertainableProcessing as a reactant
  • •Preservative in Food, beverage, and tobacco product manufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Process regulators in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Anti-static agent in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Dye in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant
  • •pH regulating agent in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •pH regulating agent in Textiles, apparel, and leather manufacturing (51%)Processing—incorporation into article
  • •Softener and conditioner in Rubber Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS127-09-3
PubChem CID517045
DTXSIDDTXSID2027044
FormulaC2H3NaO2
Mol. Weight82.03 g/mol
SMILESCC(=O)[O-].[Na+]

Data Sources

DTXSID20270442026-04-06

https://doi.org/10.23645/epacomptox.5588566

Archive: data/sources/comptox/dsstox_identifiers.csv

5170452026-04-06

https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/517045/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON

Archive: data/sources/pubchem_properties/517045.json

127-09-32026-04-24

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr.csv

CAS 127-09-32026-06-13

https://api.fda.gov/drug/shortages.json

Archive: data/sources/fda/shortages/shortages.json

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